Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Simultaneous induction of mutagenic and cancerogenic effects in T x HT mice with transplacental ethylnitrosourea treatment.

Teratogenesis, carcinogenesis, and mutagenesis - 1 Jan 1990

Schmahl W, Neuhäuser-Klaus A, Leierseder-Bauer M, Luz A

Abstract excerpt

The relationship between mutagenesis and carcinogenesis was investigated in T x HT crossbred mice using diaplacental application of ethylnitrosourea (ENU) at different stages of embryonal development. Mutagenesis was detected by induction of coat color spots, and the carcinogenic response was investigated in a long-term follow-up study of the F1-generation. The animals were particularly sensitive to induction of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinogens
Share to Ethylnitrosourea

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mosaicism

Share to Mutagens

Share to Mutation

Share to Neoplasms, Experimental

Share to Pregnancy

Source

Identifiers

PMID: 1980033
DOI: 10.1002/tcm.1770100404

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Simultaneous induction of mutagenic and cancerogenic effects in T x HT mice with transplacental ethylnitrosourea treatment.PMID 1980033Read ↗

Embryonic mutation as a possible cause of in utero carcinogenesis in mice revealed by postnatal treatment with 12-O-tetradecanoylphorbol-13-acetate.Semantic proximity Read ↗

Consideration of the liver of embryonic lacZ transgenic mice as an analogue of the mouse coat colour spot test: preliminary data and technical problems.Semantic proximity Read ↗

N-nitrosomethylurea-induced carcinogenesis in the progeny of male rats of different ages.Semantic proximity Read ↗

Mutagenicities of N-nitrosodimethylamine and N-nitrosodiethylamine in Drosophila and their relationship to the levels of O-alkyl adducts in DNA.Semantic proximity Read ↗

Combined assessment of transgenic rodent gene mutation and micronuclei formation by benzo[a]pyrene, N-ethyl-N-nitrosourea, 2,4-diaminotoluene and ethyl carbamate.Semantic proximity Read ↗

Transgenerational carcinogenesis: induction and transmission of genetic alterations and mechanisms of carcinogenesis.Semantic proximity Read ↗

Mechanisms of multistep carcinogenesis and carcinogen risk assessment.Semantic proximity Read ↗

Relevance of Carcinogen-Induced Preclinical Cancer ModelsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.