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Article

Circadian disruption induced by light-at-night accelerates aging and promotes tumorigenesis in rats

2 Oct 2009

Abstract excerpt

We evaluated the effect of various light/dark regimens on the survival, life span and tumorigenesis in rats. Two hundred eight male and 203 females LIO rats were subdivided into 4 groups and kept at various light/dark regimens: standard 12:12 light/dark (LD); natural lighting of the North-West of Russia (NL); constant light (LL), and constant darkness (DD) since the age of 25 days until natural death. We found...

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PMID: 20157558
DOI: 10.18632/aging.100092

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