Article
Estrogen receptor (ER) α mutations in breast cancer: hidden in plain sight.
Breast cancer research and treatment - 1 Feb 2014
Fuqua Suzanne A W, Gu Guowei, Rechoum Yassine
Abstract excerpt
The idea that somatic ERα mutations could play an important role in the evolution of hormone-dependent breast cancers was proposed some years ago (Fuqua J Mammary Gland Biol Neoplasia 6(4):407-417, 2001; Dasgupta et al. Annu Rev Med 65:279-292, 2013), but has remained controversial until recently. A significant amount of new data has confirmed these initial observations and shown their significance, along with...
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