Sequences upstream of the-35 hexamer of rrnB P1 affect promoter strength and upstream activation.

doi:10.1016/0167-4781(90)90186-6

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Article

Sequences upstream of the-35 hexamer of rrnB P1 affect promoter strength and upstream activation.

Biochimica et biophysica acta - 27 Aug 1990

Josaitis C A, Gaal T, Ross W, Gourse R L

Abstract excerpt

Transcription from Escherichia coli ribosomal RNA promoters is increased about 20-fold in vivo by a DNA sequence (the Upstream Activation Region, UAR) located upstream of the -35 conserved hexamer. The UAR stimulates transcription through two mechanisms: one which involves binding of the Fis prot...

Topics

Base Sequence
Binding Sites
Carrier Proteins
DNA-Binding Proteins
Escherichia coli
Escherichia coli Proteins
Factor For Inversion Stimulation Protein
Gene Expression Regulation, Bacterial
Integration Host Factors
Molecular Sequence Data
Mutation
Promoter Regions, Genetic
Restriction Mapping
Sequence Homology, Nucleic Acid
Transcription, Genetic
beta-Galactosidase

Source

Open in PubMed

Identifiers

PMID: 2119814
DOI: 10.1016/0167-4781(90)90186-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2119814-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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