Article
Transforming growth factor beta modulates C3 and factor B biosynthesis and complement receptor 3 expression in cultured human monocytes.
Journal of leukocyte biology - 1 Feb 1995
Høgåsen A K, Hestdal K, Høgåsen K, Abrahamsen T G
Abstract excerpt
Complement biosynthesis in monocytes is stimulated by different pathogens and modulated by a variety of cytokines, but little is known about the possible effect of transforming growth factor beta (TGF-beta) on this monocyte function. We therefore studied the effect of TGF-beta 1 and TGF-beta 2 on...
Topics
- Adjuvants, Immunologic
- Animals
- Antibodies
- Antigens, Surface
- Candida albicans
- Cells, Cultured
- Complement C3
- Complement Factor B
- Cycloheximide
- Granulocyte-Macrophage Colony-Stimulating Factor
- Humans
- Lipopolysaccharides
- Monocytes
- Phenotype
- Receptors, Complement
- Secretory Rate
- Transforming Growth Factor beta
