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Article

Mycobacterium tuberculosis infection in complement receptor 3-deficient mice.

Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2000

Hu C, Mayadas-Norton T, Tanaka K, Chan J, Salgame P

Abstract excerpt

Complement receptor type 3 (CR3) present on macrophages is used by Mycobacterium tuberculosis as one of its major phagocytic receptors. In this study, we examined the in vivo significance of CR3-mediated phagocytosis on the pathogenesis of disease caused by M. tuberculosis. The outcome of tuberculous infection in mice deficient in the CD11b subunit of CR3 (CR3-/-) on a mixed 129SV and C57BL background and control...

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Source

Identifiers

PMID: 10946287
DOI: 10.4049/jimmunol.165.5.2596

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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