Transforming growth factor-beta and interleukin-10, but not interleukin-4, down-regulate procoagulant activity and tissue factor expression in human monocyte-derived macrophages.

doi:10.1016/0049-3848(95)90178-i

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Article

Transforming growth factor-beta and interleukin-10, but not interleukin-4, down-regulate procoagulant activity and tissue factor expression in human monocyte-derived macrophages.

Thrombosis research - 1 Dec 1994

Jungi T W, Brcic M, Eperon S, Albrecht S

Abstract excerpt

The effect of IL-4, IL-10, and TGF-beta on expression of procoagulant activity (PCA) and of surface-associated tissue factor (TF) by human monocyte-derived macrophages was determined. Monocytes were allowed to mature to macrophages in teflon bags, and were primed either in suspension cultures, or...

Topics

Blood Coagulation Factors
Cell Line
Cytokines
Down-Regulation
Humans
Interleukin-10
Interleukin-4
Lipopolysaccharides
Macrophages
Monocytes
Phenotype
Recombinant Proteins
Thromboplastin
Transforming Growth Factor beta

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PMID: 7900094
DOI: 10.1016/0049-3848(95)90178-i

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7900094-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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