Increased retention of small chromosomes in a novel yeast mutant.

doi:10.1093/oxfordjournals.jbchem.a124582

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Article

Increased retention of small chromosomes in a novel yeast mutant.

Journal of biochemistry - 1 Sept 1994

Wada M, Kohno K, Kano Y, Mitsui H, Kuwano M, Schlessinger D, Imamoto F

Abstract excerpt

MSC201 and MSC202 are novel yeast mutant strains in which a 10-kb linear yeast artificial chromosome (YAC) was stably maintained in unselective medium during mitotic cell division. After culturing for 35 cycles of cell division, about 50% of MSC cells retain YAC3 DNA, compared to 0.001% of the wi...

Topics

Chromosomes, Artificial, Yeast
Molecular Weight
Mutation
Saccharomyces cerevisiae

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