Article
Mouse models for four types of Waardenburg syndrome.
Pigment cell research - 1 Oct 2003
Tachibana Masayoshi, Kobayashi Yasuhito, Matsushima Yoshibumi
Abstract excerpt
Waardenburg syndrome (WS) is an auditory-pigmentary syndrome caused by a deficiency of melanocytes and other neural crest-derived cells. Depending on a variety of symptoms associated with the auditory-pigmentary symptoms, WS is classified into four types: WS type 1 (WS1), WS2, WS3, and WS4. Six genes contributing to this syndrome--PAX3, SOX10, MITF, SLUG, EDN3 and EDNRB--have been cloned so far, all of them...
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