Purification and characterization of the platelet-aggregating sialoglycoprotein gp44 expressed by highly metastatic variant cells of mouse colon adenocarcinoma 26.

Abstract excerpt

A platelet-aggregating sialoglycoprotein with a molecular weight of 44,000 (gp44) was immunochemically purified from highly metastatic mouse adenocarcinoma cells. The rat monoclonal antibody (mAb) 8F11 used in the purification procedure has been generated previously against NL-17 cells derived fr...

Topics

• Adenocarcinoma
• Animals
• Antibodies, Monoclonal
• Antigens, Neoplasm
• Blood Platelets
• Carbohydrates
• Cells, Cultured
• Chromatography, Affinity
• Colonic Neoplasms
• Female
• Genetic Variation
• Immunochemistry
• Mice
• Mice, Inbred BALB C
• Neoplasm Metastasis
• Platelet Aggregation
• Sialoglycoproteins
• Structure-Activity Relationship