Binding of histone H1e-c variants to CpG-rich DNA correlates with the inhibitory effect on enzymic DNA methylation.

doi:10.1042/bj3050739

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Article

Binding of histone H1e-c variants to CpG-rich DNA correlates with the inhibitory effect on enzymic DNA methylation.

The Biochemical journal - 1 Feb 1995

Santoro R, D'Erme M, Mastrantonio S, Reale A, Marenzi S, Saluz H P, Strom R, Caiafa P

Abstract excerpt

Within the H1 histone family, only some fractions enriched in the H1e-c variants are effective in causing a marked inhibition, in vitro, of enzymic DNA methylation and, in gel retardation and Southwestern blot experiments, in binding double-stranded (ds) CpG-rich oligonucleotides. Both the 6-CpG...

Topics

Animals
Base Sequence
Binding Sites
Cattle
DNA
DNA Modification Methylases
Dinucleoside Phosphates
Genetic Variation
Histones
Methylation
Molecular Sequence Data

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