Article
Specific variants of H1 histone regulate CpG methylation in eukaryotic DNA.
Gene - 19 May 1995
Strom R, Santoro R, D'Erme M, Mastrantonio S, Reale A, Marenzi S, Zardo G, Caiafa P
Abstract excerpt
Upon HPLC fractionation of human placenta or calf thymus H1 histone preparations, only some fractions enriched in the H1e-c variants were able to exert a severe inhibition on in vitro enzymatic DNA methylation. These fractions, though similar to the other variants in interacting with genomic DNA,...
Topics
- Animals
- Base Sequence
- Cattle
- Chromatin
- DNA
- Dinucleoside Phosphates
- Female
- Genetic Variation
- Histones
- Humans
- Methylation
- Molecular Sequence Data
- Oligodeoxyribonucleotides
- Placenta
- Pregnancy
- Thymus Gland