Article

CpG Island DNA Has a Low Affinity for Nucleosome Formation

2025-11-20

Abstract excerpt

CpG islands in vertebrate genomes are associated not only with housekeeping genes but also with some tissue-restricted genes, including those that comprise the alpha-like globin gene clusters of humans and rabbits. The facts that CpG islands are unmethylated in all tissues (even those not expressing the genes) and that they adopt a unique chromatin structure may have influenced the evolution of mechanisms by which...

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Literature Corpus work: a9fe5a01-0d57-588c-bed7-28879888a854
DOI: 10.20944/preprints202511.1447.v1

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