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Article

Molecular genetics of Aspergillus pathogenicity.

Antonie van Leeuwenhoek - 1 Jan 1994

Holden D W, Tang C M, Smith J M

Abstract excerpt

Aspergillus fumigatus is the most frequent cause of Invasive Pulmonary Aspergillosis (IPA), a life-threatening disease of immunosuppressed patients. In addition to a number of general physiological attributes of this fungus, it has been suggested that extracellular elastase and toxins might facilitate its growth in lung tissue. We have investigated the roles of two extracellular proteins, an alkaline protease...

Topics

4-Aminobenzoic Acid
Animals
Aspergillosis
Aspergillus
Aspergillus fumigatus
Aspergillus nidulans
Disease Models, Animal
Humans
Lung Diseases, Fungal
Lysine
Mice
Molecular Biology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Virulence

Source

Identifiers

PMID: 7847892
DOI: 10.1007/BF00871953

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7847892-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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