Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deletion of the Aspergillus fumigatus Gene Encoding the Ras-Related Protein RhbA Reduces Virulence in a Model of Invasive Pulmonary Aspergillosis

18 Apr 2003

Abstract excerpt

Aspergillus fumigatus is the predominant mold pathogen in patients who lack functional innate immunity. The A. fumigatus rhbA gene was first identified as a transcript that was upregulated when the organism was grown in the presence of mammalian cells. To gain insight into the function of rhbA in the growth and pathogenesis of A. fumigatus, we constructed a strain that lacks a functional rhbA gene. The Delta rhbA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal resistance and susceptibility
Share to Fungal and yeast genetics research
Share to Mycotoxins in Agriculture and Food

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12704156
DOI: 10.1128/iai.71.5.2819-2826.2003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deletion of the Aspergillus fumigatus Gene Encoding the Ras-Related Protein RhbA Reduces Virulence in a Model of Invasive Pulmonary AspergillosisPMID 12704156Read ↗

Identification and Characterization of a Novel Aspergillus fumigatus Rhomboid Family Putative Protease, RbdA, Involved in Hypoxia Sensing and Virulence.Semantic proximity Read ↗

A fungus-specific ras homolog contributes to the hyphal growth and virulence of Aspergillus fumigatus.Semantic proximity Read ↗

RbdB, a Rhomboid Protease Critical for SREBP Activation and Virulence in <i>Aspergillus fumigatus</i>Semantic proximity Read ↗

A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatusSemantic proximity Read ↗

Ras subfamily GTPases regulate development, aflatoxin biosynthesis and pathogenicity in the fungus Aspergillus flavusSemantic proximity Read ↗

The Small GTPase RacA Mediates Intracellular Reactive Oxygen Species Production, Polarized Growth, and Virulence in the Human Fungal Pathogen Aspergillus fumigatusSemantic proximity Read ↗

Using bar-seq as a proxy to study population dynamics of Aspergillus fumigatus deletion libraries during infection of mammalian cellsSemantic proximity Read ↗

A family of secreted pathogenesis-related proteins in Candida albicans.Semantic proximity Read ↗

MybA, a transcription factor involved in conidiation and conidial viability of the human pathogen Aspergillus fumigatusSemantic proximity Read ↗

Transcriptional profiling identifies a role for BrlA in the response to nitrogen depletion and for StuA in the regulation of secondary metabolite clusters in Aspergillus fumigatus.Semantic proximity Read ↗

Overexpression of the Aspergillus fumigatus Small GTPase, RsrA, Promotes Polarity Establishment during GerminationSemantic proximity Read ↗

Essential gene identification and drug target prioritization in Aspergillus fumigatus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.