Article
LaeA, a regulator of morphogenetic fungal virulence factors.
Eukaryotic cell - 1 Sept 2005
Bok Jin Woo, Balajee S Arunmozhi, Marr Kieren A, Andes David, Nielsen Kristian Fog, Frisvad Jens C, Keller Nancy P
Abstract excerpt
Opportunistic animal and plant pathogens, well represented by the genus Aspergillus, have evolved unique mechanisms to adapt to and avoid host defenses. Aspergillus fumigatus, an increasingly serious pathogen owing to expanding numbers of immunocompromised patients, causes the majority of human infections; however, an inability to identify bona fide virulence factors has impeded therapeutic advances. We show that...
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