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Article

The role of acetaldehyde in alcohol-associated cancer of the gastrointestinal tract.

Novartis Foundation symposium - 1 Jan 2007

Seitz Helmut K, Homann Nils

Abstract excerpt

Acetaldehyde has been classified as a carcinogen in experimental animal research. Acetaldehyde is highly toxic, mutagenic and carcinogenic. Acetaldehyde causes point mutations, sister chromatid exchanges and gross chromosomal aberrations. In the liver, acetaldehyde binds to DNA and the formation of stable adducts represents one mechanism by which acetaldehyde could trigger the occurrence of replication errors...

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Source

Identifiers

PMID: 17590990
DOI: 10.1002/9780470511848.ch8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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