Breakpoint analysis: precise localization of genetic markers by means of nonstatistical computation using relatively few genotypes.

Article

Breakpoint analysis: precise localization of genetic markers by means of nonstatistical computation using relatively few genotypes.

American journal of human genetics - 1 Feb 1995

Elsner T I, Albertsen H, Gerken S C, Cartwright P, White R

Abstract excerpt

Placing new markers on a previously existing genetic map by using conventional methods of multilocus linkage analysis requires that a large number of reference families be genotyped. This paper presents a methodology for placing new markers on existing genetic maps by genotyping only a few indivi...

Topics

Algorithms
Chromosome Mapping
Genetic Linkage
Genetic Markers
Genotype
Humans
Mathematical Computing
Meiosis
Recombination, Genetic
Reproducibility of Results
Software

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