Molecular and statistical approaches to the detection and correction of errors in genotype databases.

Article

Molecular and statistical approaches to the detection and correction of errors in genotype databases.

American journal of human genetics - 1 Nov 1993

Brzustowicz L M, Mérette C, Xie X, Townsend L, Gilliam T C, Ott J

Abstract excerpt

Errors in genotyping data have been shown to have a significant effect on the estimation of recombination fractions in high-resolution genetic maps. Previous estimates of errors in existing databases have been limited to the analysis of relatively few markers and have suggested rates in the range...

Topics

Bias
Chromosomes, Human, Pair 5
Databases, Factual
Genetic Linkage
Genetic Markers
Genotype
Humans
Models, Genetic
Molecular Biology
Quality Control
Statistics as Topic

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