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Article

Accommodating chromosome inversions in linkage analysis.

American journal of human genetics - 1 Aug 2006

Chen Gary K, Slaten Erin, Ophoff Roel A, Lange Kenneth

Abstract excerpt

This work develops a population-genetics model for polymorphic chromosome inversions. The model precisely describes how an inversion changes the nature of and approach to linkage equilibrium. The work also describes algorithms and software for allele-frequency estimation and linkage analysis in the presence of an inversion. The linkage algorithms implemented in the software package Mendel estimate recombination...

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Identifiers

PMID: 16826515
DOI: 10.1086/505540
PMCID: PMC1559487

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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