Article
In vivo evidence for the involvement of anionic phospholipids in initiation of DNA replication in Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America - 31 Jan 1995
Xia W, Dowhan W
Abstract excerpt
In vitro, anionic phospholipids can reactivate inactivated DnaA protein, which is essential for initiation of DNA replication at the oriC site of Escherichia coli [Sekimizu, K. & Kornberg, A. (1988) J. Biol. Chem. 263, 7131-7135]. Mutations in the pgsA gene (encoding phosphatidylglycerophosphate...
Topics
- Anions
- Bacterial Proteins
- DNA Replication
- DNA-Binding Proteins
- Escherichia coli
- Genes, Bacterial
- Models, Genetic
- Mutation
- Phospholipids
- Phosphotransferases
- Plasmids
- Replication Origin
- Ribonuclease H
- Suppression, Genetic