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Article

Molecular mechanism for functional interaction between DnaA protein and acidic phospholipids: identification of important amino acids.

The Journal of biological chemistry - 9 Mar 2001

Makise M, Mima S, Tsuchiya T, Mizushima T

Abstract excerpt

DnaA protein, the initiator of chromosomal DNA replication in Escherichia coli, seems to be reactivated from the ADP-bound form to its ATP-bound form through stimulation of ADP release by acidic phospholipids such as cardiolipin. We previously reported that two potential amphipathic helices (Lys-327 to Ile-344 and Asp-357 to Val-374) of DnaA protein are involved in the functional interaction between DnaA and...

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Source

Identifiers

PMID: 11102450
DOI: 10.1074/jbc.M009643200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Molecular mechanism for functional interaction between DnaA protein and acidic phospholipids: identification of important amino acids.PMID 11102450Read ↗

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