Viability of an Escherichia coli pgsA null mutant lacking detectable phosphatidylglycerol and cardiolipin.

Abstract excerpt

Phosphatidylglycerol, the most abundant acidic phospholipid in Escherichia coli, has been considered to play specific roles in various cellular processes and is believed to be essential for cell viability. It is functionally replaced in some cases by cardiolipin, another abundant acidic phospholipid derived from phosphatidylglycerol. However, we now show that a null pgsA mutant is viable, if the major outer...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cardiolipins
• Share to Escherichia coli
• Share to Mutation