Article
The proliferation of multiple myeloma colonies (MY-CFUc) in vitro is independent of prognosis and is not associated with mutated N- or K-ras alleles in human bone marrow aspirates.
British journal of cancer - 1 Feb 1995
Millar B C, Bell J B, Barfoot R, Everard M
Abstract excerpt
During the period September 1987 to March 1993 the proliferation of myeloma cells as colonies (MY-CFUc) in vitro was examined in bone marrow aspirates from 43 patients with multiple myeloma and two patients with Waldenström's macroglobulinaemia. Twenty-four samples from 45 patients, of whom three...
Topics
- Alleles
- Base Sequence
- Bone Marrow
- Cell Division
- DNA Mutational Analysis
- DNA, Neoplasm
- Female
- Genes, ras
- Humans
- Male
- Molecular Sequence Data
- Multiple Myeloma
- Polymerase Chain Reaction
- Prognosis
- Retrospective Studies
- Survival Analysis
- Tumor Cells, Cultured
- Tumor Stem Cell Assay