A serum-free culture method for myeloma progenitors in vitro: proliferative and immunophenotypic characteristics.

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Article

A serum-free culture method for myeloma progenitors in vitro: proliferative and immunophenotypic characteristics.

Experimental hematology - 1 Feb 1990

Rhodes E G, Olive C, Flynn M P

Abstract excerpt

Methods for forming multiple myeloma (MM) colonies are difficult because nonproliferative, but viable, plasma cells can survive for several weeks in culture and because MM cells tend to clump readily, forming pseudo-colonies. The present study describes a method for growing pure myeloma colonies...

Topics

Antigens, Viral
Cell Transformation, Neoplastic
Colony-Forming Units Assay
Culture Media
Epstein-Barr Virus Nuclear Antigens
Fluorescent Antibody Technique
Growth Substances
Humans
Mitosis
Multiple Myeloma
Neoplastic Stem Cells
Phenotype
Tumor Cells, Cultured
Tumor Stem Cell Assay

Source

Open in PubMed

Identifiers

PMID: 2406157

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2406157-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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