Article
A serum-free culture method for myeloma progenitors in vitro: proliferative and immunophenotypic characteristics.
Experimental hematology - 1 Feb 1990
Rhodes E G, Olive C, Flynn M P
Abstract excerpt
Methods for forming multiple myeloma (MM) colonies are difficult because nonproliferative, but viable, plasma cells can survive for several weeks in culture and because MM cells tend to clump readily, forming pseudo-colonies. The present study describes a method for growing pure myeloma colonies in serum-free conditions in which genuine myeloma growth is unequivocally demonstrated. Growth was observed in 17 of 32...
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