Article
Circulating megakaryocyte progenitors in myeloproliferative disorders are hypersensitive to interleukin‐3
1 Apr 1993
Abstract excerpt
Previous studies have reported that megakaryocyte progenitors in myeloproliferative disorders (MPD) formed spontaneous megakaryocyte colonies without the addition of megakaryocyte colony-stimulating factor (Meg-CSF). To determine whether this spontaneous colony formation is due to autocrine proliferation of MPD megakaryocyte progenitors or to hypersensitivity to Meg-CSF that might exist in the culture system, we...
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