The role of SRY in mammalian sex determination.

doi:10.1111/j.1442-200x.1996.tb03512.x

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Article

The role of SRY in mammalian sex determination.

Acta paediatrica Japonica : Overseas edition - 1 Aug 1996

Fechner P Y

Abstract excerpt

The gene SRY (sex determining region of the Y), located at the distal region of the short arm of the Y chromosome, is necessary for male sex determination in mammals. SRY initiates the cascade of steps necessary to form a testis from an undifferentiated gonad. The SRY gene encodes an HMG (High Mo...

Topics

Animals
DNA-Binding Proteins
Disorders of Sex Development
Female
Genes, Homeobox
Gonadal Dysgenesis
High Mobility Group Proteins
Humans
Male
Mutation
Nuclear Proteins
Sex Determination Analysis
Sex Differentiation
Sex-Determining Region Y Protein
Transcription Factors
Y Chromosome

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