Characterization of a null mutation in ace-1, the gene encoding class A acetylcholinesterase in the nematode Caenorhabditis elegans.

doi:10.1016/0014-5793(94)01343-y

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Article

Characterization of a null mutation in ace-1, the gene encoding class A acetylcholinesterase in the nematode Caenorhabditis elegans.

FEBS letters - 9 Jan 1995

Talesa V, Culetto E, Schirru N, Bernardi H, Fedon Y, Toutant J P, Arpagaus M

Abstract excerpt

Two genes (ace-1 and ace-2) encode two major classes (A and B) of acetylcholinesterase (AChE) in the nematode Caenorhabditis elegans. A null mutation in ace-1 (allele p1000) suppresses all acetylcholinesterase activity of class A. We have identified an opal mutation TGG (W99)-->TGA (Stop) as the...

Topics

Acetylcholinesterase
Animals
Base Sequence
Caenorhabditis elegans
Genes, Helminth
Molecular Sequence Data
Mutation
Oligodeoxyribonucleotides
RNA, Messenger

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