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Article

Production of null mutants in the major intestinal esterase gene (ges-1) of the nematode Caenorhabditis elegans.

Genetics - 1 Jul 1990

McGhee J D, Birchall J C, Chung M A, Cottrell D A, Edgar L G, Svendsen P C, Ferrari D C

Abstract excerpt

The ges-1 gene of the nematode Caenorhabditis elegans codes for a nonspecific carboxylesterase that is expressed only in the intestinal lineage. This esterase has turned out to be a convenient biochemical marker for lineage-specific differentiation. In the present paper, we describe the production of several C. elegans strains that lack detectable activity of the ges-1 esterase. To isolate these ges-1 null...

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Identifiers

PMID: 2379823
DOI: 10.1093/genetics/125.3.505
PMCID: PMC1204078

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Source receipt: pubmed, retrieved 7 Sept 2026.

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