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Article

Differential positive and negative transcriptional regulation by tamoxifen.

Endocrinology - 1 Feb 1995

Ramkumar T, Adler S

Abstract excerpt

Tamoxifen, a nonsteroidal antiestrogen and breast cancer chemotherapeutic, exhibits both estrogen agonist and antagonist properties. Rat GC3 cells grown under estrogen-free conditions were analyzed for the expression of model luciferase reporter genes, either positively or negatively regulated by estrogens. Expression assays adding tamoxifen alone or in combination with 17 beta-estradiol were performed to...

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Identifiers

PMID: 7835285
DOI: 10.1210/endo.136.2.7835285

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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