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Article

Agonistic and synergistic activity of tamoxifen in a yeast model system.

Biochemical pharmacology - 15 Jan 2000

Graumann K, Jungbauer A

Abstract excerpt

The background of agonist/antagonist behaviour of the non-steroidal antiestrogen tamoxifen is still not fully understood. Depending on cell type, its activities range from full agonistic to antagonistic in different tissues. We investigated the transactivational properties of tamoxifen in a basic yeast model system which reconstitutes ligand-dependent human estrogen receptor-alpha (hER alpha) gene activation....

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Source

Identifiers

PMID: 10810452
DOI: 10.1016/s0006-2952(99)00308-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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