Article
Identical allelic loss on chromosome 11q13 in microdissected in situ and invasive human breast cancer.
Cancer research - 1 Feb 1995
Zhuang Z, Merino M J, Chuaqui R, Liotta L A, Emmert-Buck M R
Abstract excerpt
Human breast carcinoma is thought to develop through progressive stages from atypical hyperplasias to in situ carcinoma and finally to invasive and metastatic cancer. In situ breast carcinoma consists of small, isolated neoplastic foci which cannot be selectively studied by conventional methods....
Topics
- Alleles
- Breast Neoplasms
- Carcinoma in Situ
- Chromosome Deletion
- Chromosome Mapping
- Chromosomes, Human, Pair 11
- DNA, Neoplasm
- Gene Deletion
- Genes, Tumor Suppressor
- Genetic Markers
- Humans
- Neoplasm Invasiveness
- Polymerase Chain Reaction
- Polymorphism, Genetic
