Article
Dimerization of beta B2-crystallin: the role of the linker peptide and the N- and C-terminal extensions.
Protein science : a publication of the Protein Society - 1 Sept 1994
Trinkl S, Glockshuber R, Jaenicke R
Abstract excerpt
beta B2- and gamma B-crystallins of vertebrate eye lens are 2-domain proteins in which each domain consists of 2 Greek key motifs connected by a linker peptide. Although the folding topologies of beta B2- and gamma B-domains are very similar, gamma B-crystallin is always monomeric, whereas beta B2-crystallin associates to homodimers. It has been suggested that the linker or the protruding N- and C-terminal arms...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.