Article
Dinucleotide repeats in the human surfactant protein-B gene and respiratory-distress syndrome.
The Biochemical journal - 15 Jan 1995
Floros J, Veletza S V, Kotikalapudi P, Krizkova L, Karinch A M, Friedman C, Buchter S, Marks K
Abstract excerpt
Pulmonary surfactant, a lipoprotein complex, is essential for normal lung function, and deficiency of surfactant can result in respiratory-distress syndrome (RDS) in the prematurely born infant. Some studies have pointed towards a genetic contribution to the aetiology of RDS. Because the surfactant protein B (SP-B) is important for optimal surfactant function and because it is involved in the pathogenesis of...
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