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Article

Molecular changes in virulent mutants arising from avirulent avian influenza viruses during replication in 14-day-old embryonated eggs.

Virology - 10 Jan 1995

Horimoto T, Kawaoka Y

Abstract excerpt

The emergence of virulent avian influenza viruses in poultry is unpredictable. To gain insight into the mechanism for this event, we sought to identify the molecular changes in virulent mutants that occur during replication in 14-day-old embryonated chicken eggs. After three passages in 14-day-ol...

Topics

Amino Acid Sequence
Animals
Base Sequence
Chick Embryo
DNA, Complementary
Glycosylation
Hemagglutinin Glycoproteins, Influenza Virus
Hemagglutinins, Viral
Influenza A virus
Molecular Sequence Data
Mutation
Virulence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Virus Replication

Source

Identifiers

PMID: 7831837
DOI: 10.1016/s0042-6822(95)80004-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7831837-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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