A possible mechanism for selection of virulent avian influenza A viruses in 14-day-old embryonated eggs.

doi:10.1292/jvms.60.273

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Article

A possible mechanism for selection of virulent avian influenza A viruses in 14-day-old embryonated eggs.

The Journal of veterinary medical science - 1 Feb 1998

Horimoto T, Kawaoka Y

Abstract excerpt

The emergence of virulent avian influenza viruses in poultry is unpredictable. To gain insight into the mechanism of this event, we previously examined the possible role of older (14-day-old) embryonated eggs, in which virulent mutants were preferably selected (Horimoto and Kawaoka, Virology 206:...

Topics

Allantois
Animals
Chick Embryo
Chickens
Endopeptidases
Glycosylation
Hemagglutinins, Viral
Influenza A virus
Kinetics
Mutation
Polymerase Chain Reaction
Substrate Specificity
Virulence
Virus Replication

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