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Article

Transcriptional regulation of insulin receptor gene promoter in rat hepatocytes.

Biochemical and biophysical research communications - 9 Feb 2001

Fukuda H, Noguchi T, Iritani N

Abstract excerpt

To investigate the DNA regulatory sequences -618 to -593 (initiator ATG is +1) of the insulin receptor (IR) promoter required for IR gene expression, primary cultured hepatocytes of rats were transfected with plasmids containing the 5'-flanking sequences of the rat IR gene fused to the luciferase gene. When three copies of the nucleotides -618 to -593 of the IR promoter were transfected, the reporter activity was...

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PMID: 11162666
DOI: 10.1006/bbrc.2001.4260

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FAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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