Apolipoprotein E-immunoreactivity in aged rhesus monkey cortex: colocalization with amyloid plaques.

doi:10.1016/0197-4580(94)00064-6

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Article

Apolipoprotein E-immunoreactivity in aged rhesus monkey cortex: colocalization with amyloid plaques.

Neurobiology of aging - 1 Jan 2000

Mufson E J, Benzing W C, Cole G M, Wang H, Emerich D F, Sladek J R, Morrison J H, Kordower J H

Abstract excerpt

In the present study, we examined the relationship between ApoE and amyloid containing profiles within the cerebral cortex of young, middle aged, and aged Rhesus monkeys. Polymerase chain reaction analysis revealed a pattern consistent with the ApoE e4 phenotype in the rhesus monkey similar to th...

Topics

Aging
Amyloid
Amyloidosis
Animals
Apolipoproteins E
Cerebral Cortex
Female
Genotype
Hippocampus
Immunohistochemistry
Macaca mulatta
Male
Phenotype

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