Article
Human APOE protein localized in brains of transgenic mice.
Neuroscience letters - 15 Nov 1996
Bowman B H, Yang F, Buchanan J M, Adrian G S, Martinez A O, Jansen L, Zhao M, Atherton S L, Hixson J E
Abstract excerpt
Transgenic mice carrying the three common human apolipoprotein E (APOE) alleles have been developed. In this study, brains of the transgenic mice have been analyzed by in situ histohybridization, immunohistochemistry, and immunoblots to determine sites of gene expression, to identify specific brain cells associated with human apoE protein, and to determine the relative concentrations of the human apoE. Results...
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