Article
Association of apolipoprotein E-e4 and dementia declines with age.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 Oct 2014
Valerio Daniel, Raventos Henriette, Schmeidler James, Beeri Michal S, Villalobos Lara Mora, Bolaños-Palmieri Patricia, Carrión-Baralt José R, Fornaguera Jaime, Silverman Jeremy M
Abstract excerpt
OBJECTIVE: To study the association of dementia with apolipoprotein E-e4 (APOE-e4) and its interaction with age in a nonagenarian Costa Rican group (N-sample) and a general elderly contrast group (GE-sample). METHODS: In both case-control studies, participants were cognitively intact or diagnosed with dementia. The N-sample (N = 112) was at least age 90 years; the GE-sample (N = 98) was at least age 65 years....
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