Apolipoprotein E4 and beta amyloid in senile plaques and cerebral blood vessels of aged rhesus monkeys.

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Article

Apolipoprotein E4 and beta amyloid in senile plaques and cerebral blood vessels of aged rhesus monkeys.

The American journal of pathology - 1 Jun 1994

Poduri A, Gearing M, Rebeck G W, Mirra S S, Tigges J, Hyman B T

Abstract excerpt

Recent studies of late onset familial and sporadic Alzheimer's disease (AD) show a genetic disequilibrium between inheritance of the epsilon 4 allele of the apolipoprotein E (ApoE) gene and development of AD. beta-Amyloid (A beta)-positive senile plaques and blood vessels in AD are immunoreactive...

Topics

Aging
Alleles
Amino Acid Sequence
Amyloid beta-Peptides
Animals
Apolipoprotein E4
Apolipoproteins E
Base Sequence
Cerebral Arteries
Cerebral Veins
DNA
Disease Models, Animal
Female
Genotype
Immunohistochemistry
Macaca mulatta
Male
Molecular Sequence Data

Source

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Identifiers

PMID: 8203459
PMCID: PMC1887468

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8203459-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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