Article
Cerebrovascular amyloidosis in squirrel monkeys and rhesus monkeys: apolipoprotein E genotype.
FEBS letters - 29 Jan 1996
Morelli L, Wei L, Amorim A, McDermid J, Abee C R, Frangione B, Walker L C, Levy E
Abstract excerpt
Some neuropathological changes characteristic of aging and Alzheimer's disease (AD) in humans are present also in senescent non-human primates. The human apoE4 allele is associated with an increased risk of developing late-onset familial and sporadic AD. We found that rhesus monkeys and three sub...
Topics
- Alzheimer Disease
- Amino Acid Sequence
- Amyloidosis
- Animals
- Apolipoprotein E4
- Apolipoproteins E
- Base Sequence
- Cerebrovascular Disorders
- Deoxyribonucleases, Type II Site-Specific
- Genotype
- Humans
- Macaca mulatta
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Saimiri
- Sequence Homology, Amino Acid
- Sequence Homology, Nucleic Acid