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Article

[Morphological atypism and clinicopathological factors in colorectal adenoma and cancer using nuclear DNA content, p53 and PCNA].

Nihon Geka Gakkai zasshi - 1 Oct 1994

Yamamoto H, Yamada N, Asano G, Shoji T

Abstract excerpt

Cytofluorometric analysis of DNA content and immunohistochemical examination of p53 and PCNA were performed in colorectal adenomas, mainly borderline lesions, and cancers. Nuclear DNA content revealed aneuploidy and polyploid cells in severely atypical adenomas and cancers. Mutated p53 protein was also observed in severely atypical adenomas, especially tortuous and villous lesions and cancers. PCNA labeling index...

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Identifiers

PMID: 7823898

Genes

PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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