[Morphological atypism and clinicopathological factors in colorectal adenoma and cancer using nuclear DNA content, p53 and PCNA].

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Article

[Morphological atypism and clinicopathological factors in colorectal adenoma and cancer using nuclear DNA content, p53 and PCNA].

Nihon Geka Gakkai zasshi - 1 Oct 1994

Yamamoto H, Yamada N, Asano G, Shoji T

Abstract excerpt

Cytofluorometric analysis of DNA content and immunohistochemical examination of p53 and PCNA were performed in colorectal adenomas, mainly borderline lesions, and cancers. Nuclear DNA content revealed aneuploidy and polyploid cells in severely atypical adenomas and cancers. Mutated p53 protein wa...

Topics

Adenocarcinoma
Adenoma
Aneuploidy
Cell Nucleus
Colorectal Neoplasms
DNA, Neoplasm
Flow Cytometry
Humans
Immunohistochemistry
Mutation
Neoplasm Invasiveness
Neoplasm Metastasis
Proliferating Cell Nuclear Antigen
Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 7823898

Genes

PCNA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7823898-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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