Article
Pigmented well-differentiated hepatocellular neoplasm with beta-catenin mutation.
Hepatobiliary & pancreatic diseases international : HBPD INT - 1 Dec 2015
Souza Lara Neves, de Martino Rodrigo Bronze, Thompson Richard, Strautnieks Sandra, Heaton Nigel D, Quaglia Alberto
Abstract excerpt
According to the most recent WHO classification of hepatocellular adenomas, a small percentage of inflammatory hepatocellular adenomas presents with mutation in the beta-catenin gene and are at higher risk of malignant transformation. It has been recognized that adenoma-like hepatocellular neoplasms with focal atypia, or in unusual clinical context present with similar cytogenetic and immunohistochemistry...
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