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Article

Pathogenicity of Saccharomyces cerevisiae in complement factor five-deficient mice

1 Feb 1995

Abstract excerpt

We have previously determined the relative virulence of isolates of Saccharomyces cerevisiae on the basis of differences in proliferation and resistance to clearance in CD-1 mice. These infections were not fatal. To further characterize S. cerevisiae pathogenesis, we studied a virulent clinical isolate, YJM128, and an avirulent nonclinical isolate, Y55, in C5-deficient mice. DBA/2N mice were infected...

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PMID: 7822013
DOI: 10.1128/iai.63.2.478-485.1995

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