Article

Complex genetics cause and constrain fungal persistence in different parts of the mammalian body

2022-01-22

Abstract excerpt

Determining how genetic polymorphisms enable certain fungi to persist in mammalian hosts can improve understanding of opportunistic fungal pathogenesis, a source of substantial human morbidity and mortality. We examined the genetic basis of fungal persistence in mice using a cross between a clinical isolate and the lab reference strain of the budding yeast Saccharomyces cerevisiae . Employing chromosomally-encode...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9bb88bc9-4a74-5347-a2d2-d4b8084cf512
DOI: 10.1101/2022.01.20.477007

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Complex genetics cause and constrain fungal persistence in different parts of the mammalian bodyDOI 10.1101/2022.01.20.477007Read

Complex genetics cause and constrain fungal persistence in different parts of the mammalian body.Semantic proximity Read

Genetic Diversity of Human Fungal PathogensSemantic proximity Read

Drivers of diversification in fungal pathogen populations.Semantic proximity Read

Diverse Lineages of Candida albicans Live on Old OaksSemantic proximity Read

Diverse lineages of <i>Candida albicans</i> live on old oaksSemantic proximity Read

The Genome of the Human Pathogen Candida albicans Is Shaped by Mutation and Cryptic Sexual RecombinationSemantic proximity Read

The 100-genomes strains, an S. cerevisiae resource that illuminates its natural phenotypic and genotypic variation and emergence as an opportunistic pathogen.Semantic proximity Read

Genetics of Candida albicans, a Diploid Human Fungal PathogenSemantic proximity Read

The Genome of the Human Pathogen <i>Candida albicans</i> is Shaped by Mutation and Cryptic Sexual RecombinationSemantic proximity Read

The genetics of the many forms of diversity.Semantic proximity Read

Monogenetic causes of fungal disease: recent developments.Semantic proximity Read

Rapid Phenotypic and Genotypic Diversification After Exposure to the Oral Host Niche in Candida albicans.Semantic proximity Read