Article
The yeast BDF1 gene encodes a transcription factor involved in the expression of a broad class of genes including snRNAs.
Nucleic acids research - 11 Dec 1994
Lygerou Z, Conesa C, Lesage P, Swanson R N, Ruet A, Carlson M, Sentenac A, Séraphin B
Abstract excerpt
While screening for genes that affect the synthesis of yeast snRNPs, we identified a thermosensitive mutant that abolishes the production of a reporter snRNA at the non-permissive temperature. This mutant defines a new gene, named BDF1. In a bdf1-1 strain, the reporter snRNA synthesized before the temperature shift remains stable at the non-permissive temperature. This demonstrates that the BDF1 gene affects the...
Topics
- Amino Acid Sequence
- Base Sequence
- Chromosome Mapping
- Chromosomes, Fungal
- Cloning, Molecular
- Conserved Sequence
- Gene Dosage
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Genes, Regulator
