Article
Characterization of the LDL-A module mutants of Tva, the subgroup A Rous sarcoma virus receptor, and the implications in protein folding.
Protein science : a publication of the Protein Society - 1 Nov 2002
Wang Qing-Yin, Manicassamy Balaji, Yu Xuemei, Dolmer Klavs, Gettins Peter G W, Rong Lijun
Abstract excerpt
Tva is the cellular receptor for subgroup A Rous sarcoma virus (RSV-A), and the viral receptor function is solely determined by a 40-residue motif called the LDL-A module of Tva. In this report, an integral approach of molecular, biochemical, and biophysical techniques was used to examine the role of a well-conserved tryptophan of the LDL-A module of Tva in protein folding and ligand binding. We show that...
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