Article
Differential roles of Bcl2L12 and its short variant in breast cancer lymph node metastasis.
Oncology reports - 1 Aug 2015
Chien Shang-Tao, Yang Tzu-Feng, Yang Ming-Chang, Hsu Ching-Mei, Hong Yi-Ren, Lee Tai-Min
Abstract excerpt
Bcl2L12 plays a role in post-mitochondrial apoptosis through multiple mechanisms involving p53, αB-crystallin, caspase-3 and -7 in glioblastoma. Bcl2L12 is reported to be a good prognostic marker in breast cancer and correlated with ER and Bcl2 expression status. However, the mechanisms by which Bcl2L12 regulates apoptosis in breast cancer (BCa) remain unknown. Recent studies have shown that Bcl2L12 expression is...
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