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Article

Failure to detect Glut4-Ile383 and IR-Gln1152 variants in NIDDM (non-insulin dependent diabetes mellitus) and control subjects in an Italian population.

Human genetics - 1 Jan 1995

Esposito L, Carrera P, Pontiroli A E, Ferrari M

Abstract excerpt

Insulin receptor (IR) and insulin-responsive glucose transporter (Glut4) represent two candidate genes involved in the development of non-insulin dependent diabetes mellitus (NIDDM); detection of molecular alterations in these genes might explain their possible contribution to NIDDM. Recently, mu...

Topics

Base Sequence
DNA Primers
Diabetes Mellitus, Type 2
Glucose Transporter Type 4
Glutamine
Humans
Isoleucine
Italy
Molecular Sequence Data
Monosaccharide Transport Proteins
Muscle Proteins
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptor, Insulin

Source

Identifiers

PMID: 7814014
DOI: 10.1007/BF00225088

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7814014-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Failure to detect Glut4-Ile383 and IR-Gln1152 variants in NIDDM (non-insulin dependent diabetes mellitus) and control subjects in an Italian population.PMID 7814014Read ↗

Sequence variants in the pancreatic islet beta-cell inwardly rectifying K+ channel Kir6.2 (Bir) gene: identification and lack of role in Caucasian patients with NIDDM.Semantic proximity Read ↗

Amino acid polymorphism Gly 972 Arg in IRS-1 is not associated to lower clamp-derived insulin sensitivity in young healthy first degree relatives of patients with type 2 diabetes.Semantic proximity Read ↗

Polymorphisms of the human hexokinase II gene: lack of association with NIDDM and insulin resistance.Semantic proximity Read ↗

Lack of association between the Gly40Ser polymorphism in the glucagon receptor gene and NIDDM in Finland.Semantic proximity Read ↗

Molecular scanning of insulin-responsive glucose transporter (GLUT4) gene in NIDDM subjects.Semantic proximity Read ↗

Restricted geographical extension of the association of a glucagon receptor gene mutation (Gly40Ser) with non-insulin-dependent diabetes mellitus.Semantic proximity Read ↗

Promoter polymorphisms -359T/C and -303A/G of the catalytic subunit p110beta gene of human phosphatidylinositol 3-kinase are not associated with insulin secretion or insulin sensitivity in finnish subjects.Semantic proximity Read ↗

The beta cell glucokinase promoter variant is an unlikely risk factor for diabetes mellitus. Diabetes Incidence Study in Sweden (DISS).Semantic proximity Read ↗

Absence of the Gly40-ser mutation in the glucagon receptor gene in Japanese subjects with NIDDM.Semantic proximity Read ↗

[Insulin receptor Arg1131-->Gln: a novel mutation in the catalytic loop of insulin receptor observed in insulin resistant diabetes].Semantic proximity Read ↗

Molecular and linkage analysis of type-1 protein phosphatase catalytic beta-subunit gene: lack of evidence for its major role in insulin resistance in Pima Indians.Semantic proximity Read ↗

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